In the Latin origin, Cassio means "Cassio \c(a)-ssio\ as a boy's name is a variant of Cassius (Latin). See for meaning of Cassio.
The baby name Cassio sounds like Casshe and Cass. Other similar baby names are Caio, Cassian, Cassidy, Cassiel, Kassim, Massie and Tasso."
In the Literary origin, Cassio means "Appeared in Othello"